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Reduced L-glutathione (GSH) has the most human trial data, particularly fermentation-derived forms (Setria)

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L-carnitine was administered based on the recommendations, which did not change during the study period

According to the KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of CKD, SGLT2is are recommended as FIRST-LINE therapy for most patients with CKD 9 FARXIGA (dapagliflozin) can be initiated in adults with an eGFR as low as 25 mL/min/1.73 m 2